Quality of Life among Multidrug-Resistant Tuberculosis Patients in Southwestern Uganda

Authors

  • Byaruhanga Richard Sserioza Mbarara University of Science and Technology
  • Edgar Mugema Mulogo Mbarara University of Science and Technology
  • Vicent Batwala Mbarara University of Science and Technology
  • Otwine Tweheyo Anne Mbarara University of Science and Technology

DOI:

https://doi.org/10.47604/gjhs.3871

Keywords:

Quality of Life, Multidrug-Resistant, Tuberculosis Patients

Abstract

Purpose: The study assessed the quality of life among multidrug-resistant tuberculosis (MDR-TB) patients in Southwestern Uganda.

Methodology: A descriptive cross-sectional study was conducted among 71 adult MDR-TB patients attending Mbarara, Kabale, and Fort Portal Regional Referral Hospitals. Participants were selected using multistage sampling. Data were collected using a semi-structured questionnaire adapted from the WHOQOL-BREF and analysed using SPSS version 28, descriptive statistics, Chi-square tests, and logistic regression.

Findings: Most participants were male (76%), aged 31–50 years, and 44% had primary education. General quality of life was moderate (mean = 3.09), while functional outcomes (mean = 2.84) and overall life satisfaction (mean = 2.75) were low. Participants experienced pain, low energy, financial challenges, limited leisure, and reduced satisfaction with sleep, work, and social relationships.

Unique Contribution to Theory, Practice and Policy: The study recommends a patient-centred approach integrating TB and HIV services, directly observed therapy (DOT), psychosocial support, counselling, peer-support programmes, and nutritional care to improve the quality of life of MDR-TB patients.

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References

Amer, M., Akhlaq, M., Rafique, M., Fatima, S., Shafqat, I., Abbasi, A.H., Naqvi, S.U., Pokhrel, A., Fatima, A. and Ahmed, A., 2023. Health-related quality of life (HRQoL) in tuberculosis patients: a cross-sectional study using the EuroQoL EQ-5D-3L scale. SN Comprehensive Clinical Medicine, 5(1), p.53.

Araia, Z.Z., Mesfin, A.B., Mebrahtu, A.H., Tewelde, A.G., Tewelde, A.T. and Ngusbrhan Kidane, S., 2021. Health-related quality of life in tuberculosis patients in Eritrea: comparison among drug-susceptible and rifampicin/multidrug-resistant tuberculosis patients. Patient Related Outcome Measures, pp.205-212.

Omona, K., 2024. Treatment for multi-drug resistant tuberculosis (MDR-TB) in Uganda.

Padmashali, B., 2019. Socio-Economic and Psychological Burden of MDR-TB Patients at Ballari District-A Cross Sectional Study (Doctoral dissertation, Rajiv Gandhi University of Health Sciences (India)).

Pokam, B.D.T., Fokam, P., Njamen, T.N., Guemdjom, P.W. and Asuquo, A.E., 2020. Assessment of health-related quality of life of tuberculosis patients in Fako division, south-west region of Cameroon. Journal of Tuberculosis Research, 8(3), pp.93-110.

Sutar, R., Majumdar, A., Yadav, V., Basera, D.S. and Gupta, H., 2024. Anxiety, stress, and quality of life in patients with tuberculosis: A systematic review and meta-analysis. Industrial Psychiatry Journal, 33(1), pp.13-29.

Wang, H., Gu, J., Zhang, L. and Song, Y., 2024. Assessing the quality of life in patients with drug-resistant tuberculosis: a cross-sectional study. BMC Pulmonary Medicine, 24(1), p.303.

World Health Organization, 2020. Guidance for the surveillance of drug resistance in tuberculosis. World Health Organization.

Yadav, A., Singh, S., Sharma, R.K., Kumar, S., Singh, A.V. and Chauhan, D.S., 2022. Pattern of resistance to second line anti-tuberculosis drugs and associated risk factors among multidrug-resistant patients of pulmonary tuberculosis from Agra region of Uttar Pradesh, North India. International Journal of Health Care and Biological Sciences, pp.22-28.

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Published

2026-07-14

How to Cite

Sserioza, B., Mulogo, E., Batwala, V., & Otwine, A. (2026). Quality of Life among Multidrug-Resistant Tuberculosis Patients in Southwestern Uganda. Global Journal of Health Sciences, 11(3), 70–79. https://doi.org/10.47604/gjhs.3871

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