Chili Pepper as a Functional Food: Relevance to Lesotho
DOI:
https://doi.org/10.47604/ijf.2085Keywords:
Functional Foods, Chili peppers, Chronic Diseases, Developing countries, CapsaicinAbstract
Purpose: Although the use of chili peppers as functional foods in Lesotho is not well documented, their production and consumption have a rich historical background. Functional foods are those that serve as therapeutic agents in addition to nutrition. Previous research supports the many health benefits of consuming chili peppers, including their potential to mitigate the risk of cancer, cardiac arrhythmias, rheumatism, and chest colds. Nevertheless, these concepts have yet to translate into tangible alterations in policies and implementation strategies. Therefore, this review aims to identify potential topics for future research on Chili peppers, food, and therapeutic food product development; to improve the population's health and well-being
Methodology: This paper presents a literature analysis of existing data on chili peppers as functional foods, specifically emphasizing their applicability to Lesotho, a developing country.
Findings: Based on the analysis of the reviewed research, it can be inferred that those who regularly incorporate chili peppers into their diet exhibit a decreased risk of death from non-communicable diseases compared to those who do not.
Unique Contribution to Theory, Practice and Policy: The data presented in this review supports the classification of chili pepper as a functional food while also emphasizing the importance of investigating the effectiveness, safety, quality, development, and possible hazards of chili peppers, particularly in developing nations like Lesotho. The present study has great potential to provide novel global perspectives on the associations between chili peppers, non-communicable diseases (NCDs), and mortality to guide future research. Hence, future research endeavors must thoroughly examine the distinct impacts of chili peppers through more clinical studies. Moreover, the present review and further research will contribute to revising Lesotho's dietary guidelines and advancing functional food products, such as herbal supplements derived from chili peppers.
Downloads
References
Alonso-Villegas, R., González-Amaro, R. M., Figueroa-Hernández, C. Y., & RodrÃguez-Buenfil, I. M. (2023). The Genus Capsicum: A Review of Bioactive Properties of Its Polyphenolic and Capsaicinoid Composition. Molecules, 28(10), 4239. https://doi.org/10.3390/molecules28104239
Ao, Z., Huang, Z., & Liu, H. (2022). Spicy Food and Chili Peppers and Multiple Health Outcomes: Umbrella Review. Molecular Nutrition & Food Research, 66(23), 2200167. https://doi.org/10.1002/mnfr.202200167
Azlan, A., Sultana, S., Huei, C. S., & Razman, M. R. (2022). Antioxidant, Anti-Obesity, Nutritional and Other Beneficial Effects of Different Chili Pepper: A Review. Molecules, 27(3), 898. https://doi.org/10.3390/molecules27030898
Banwo, K., Olojede, A. O., Adesulu-Dahunsi, A. T., Verma, D. K., Thakur, M., Tripathy, S., Singh, S., Patel, A. R., Gupta, A. K., Aguilar, C. N., & Utama, G. L. (2021). Functional importance of bioactive compounds of foods with Potential Health Benefits: A review on recent trends. Food Bioscience, 43, 101320. https://doi.org/10.1016/j.fbio.2021.101320
Barboza, G. E., GarcÃa, C. C., Bianchetti, L. D. B., Romero, M. V., & Scaldaferro, M. (2022). Monograph of wild and cultivated chili peppers (Capsicum L., Solanaceae). PhytoKeys, 200, 1-423. https://doi.org/10.3897/phytokeys.200.71667
Baumann, S. (2015). Antimicrobial Properties of Exotic Chili Peppers Against Common Food Pathogens. https://hdl.handle.net/11299/171475
Bertao, M. R., Moraes, M. C., Palmieri, D. A., Pereira Si, L., & Goncalves, R. M. (2016). Cytotoxicity, Genotoxicity and Antioxidant Activity of Extracts from Capsicum spp. Research Journal of Medicinal Plants, 10(4), 265-275. https://doi.org/10.3923/rjmp.2016.265.275
Bonaccio, M., Di Castelnuovo, A., Costanzo, S., Ruggiero, E., De Curtis, A., Persichillo, M., Tabolacci, C., Facchiano, F., Cerletti, C., Donati, M. B., De Gaetano, G., Iacoviello, L., Iacoviello, L., De Gaetano, G., Donati, M. B., Iacoviello, L., Bonaccio, M., Bonanni, A., Cerletti, C., "¦ Persichillo, M. (2019). Chili Pepper Consumption and Mortality in Italian Adults. Journal of the American College of Cardiology, 74(25), 3139-3149. https://doi.org/10.1016/j.jacc.2019.09.068
Caterina, M. J., Schumacher, M. A., Tominaga, M., Rosen, T. A., Levine, J. D., & Julius, D. (1997). The capsaicin receptor: A heat-activated ion channel in the pain pathway. Nature, 389(6653), 816-824. https://doi.org/10.1038/39807
Chang, A., Rosani, A., & Quick, J. (2023). Capsaicin. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing. https://www.ncbi.nlm.nih.gov/books/NBK459168/
Chen, Y.-H., Zou, X.-N., Zheng, T.-Z., Zhou, Q., Qiu, H., Chen, Y.-L., He, M., Du, J., Lei, H.-K., & Zhao, P. (2017). High Spicy Food Intake and Risk of Cancer: A Meta-analysis of Case-control Studies. Chinese Medical Journal, 130(18), 2241-2250. https://doi.org/10.4103/0366-6999.213968
De Sá Mendes, N., & Gonçalves, É. C. (2020). The role of bioactive components found in peppers. Trends in Food Science & Technology, 99, 229-243. https://doi.org/10.1016/j.tifs.2020.02.032
Du, Q., Liao, Q., Chen, C., Yang, X., Xie, R., & Xu, J. (2019). The Role of Transient Receptor Potential Vanilloid 1 in Common Diseases of the Digestive Tract and the Cardiovascular and Respiratory System. Frontiers in Physiology, 10, 1064. https://doi.org/10.3389/fphys.2019.01064
Encyclopedia Britannica. (2020). Chili Pepper | Plant and Fruit. [online]. <https://www.britannica.com/plant/chili-pepper>
Ezekiel, C. N., Ortega-Beltran, A., Oyedeji, E. O., Atehnkeng, J., Kössler, P., Tairu, F., Hoeschle-Zeledon, I., Karlovsky, P., Cotty, P. J., & Bandyopadhyay, R. (2019). Aflatoxin in Chili Peppers in Nigeria: Extent of Contamination and Control Using Atoxigenic Aspergillus flavus Genotypes as Biocontrol Agents. Toxins, 11(7), 429. https://doi.org/10.3390/toxins11070429
Ganguly, P. (2019). Microbes in us and their role in human health and disease. NIH Natl Hum Genome Res Inst.
Gregor, D. M., Zuo, W., Fu, R., Bekker, A., & Ye, J.-H. (2019). Elevation of Transient Receptor Potential Vanilloid 1 Function in the Lateral Habenula Mediates Aversive Behaviors in Alcohol-withdrawn Rats. Anesthesiology, 130(4), 592-608. https://doi.org/10.1097/ALN.0000000000002615
Herbazest. (2022). Chili Pepper. https://www.herbazest.com/herbs/chili-pepper#nutrition. Accessed on 04/27/2020.
Huei, C. S., Azlan, A., Ismail, A., Shafie, N. H., & Sultana, S. (2020). Antioxidant and anti-obesity properties of local chilies varieties in Malaysia. Journal of Food Science and Technology, 57(10), 3677-3687. https://doi.org/10.1007/s13197-020-04400-x
Kondo, F., Hatakeyama, K., Sakai, A., Minami, M., Nemoto, K., & Matsushima, K. (2021). The pungent-variable sweet chili pepper "˜Shishito' (Capsicum annuum) provides insights regarding the relationship between pungency, the number of seeds, and gene expression involving capsaicinoid biosynthesis. Molecular Genetics and Genomics, 296(3), 591-603. https://doi.org/10.1007/s00438-021-01763-4
Lü, J.-M., Lin, P. H., Yao, Q., & Chen, C. (2010). Chemical and molecular mechanisms of antioxidants: Experimental approaches and model systems. Journal of Cellular and Molecular Medicine, 14(4), 840-860. https://doi.org/10.1111/j.1582-4934.2009.00897.x
Lv, J., Qi, L., Yu, C., Yang, L., Guo, Y., Chen, Y., Bian, Z., Sun, D., Du, J., Ge, P., Tang, Z., Hou, W., Li, Y., Chen, J., Chen, Z., & Li, L. (2015). Consumption of spicy foods and total and cause specific mortality: Population based cohort study. BMJ, h3942. https://doi.org/10.1136/bmj.h3942
Mahungu, S., & Krawinkel, M. (2006). Functional Foods - Relevance to Kenya. Kenya Coalition for Action in Nutrition.
Moreno-RamÃrez, Y., MartÃnez-Ãvila, G., González-Hernández, V., Castro-López, C., & Torres-Castillo, J. (2018). Free Radical-Scavenging Capacities, Phenolics and Capsaicinoids in Wild Piquin Chili (Capsicum annuum var. Glabriusculum). Molecules, 23(10), 2655. https://doi.org/10.3390/molecules23102655
Mudie, K., Jin, M. M., Tan, Kendall, L., Addo, J., dos-Santos-Silva, I., Quint, J., Smeeth, L., Cook, S., Nitsch, D., Natamba, B., Gomez-Olive, F. X., Ako, A., & Perel, P. (2019). Non-communicable diseases in sub-Saharan Africa: A scoping review of large cohort studies. Journal of Global Health, 9(2), 020409. https://doi.org/10.7189/jogh.09.020409
Nithya, T., Dahineeswari, V., Chowdhury, S., & Sivakumar, S. (2011). Antibacterial activity of thaaleesaadhi chooranam against human pathogens. Int J Drug Discov Herb Res.
Omolo, M. (2014). Antimicrobial Properties of Chili Peppers. Journal of Infectious Diseases and Therapy, 02(04). https://doi.org/10.4172/2332-0877.1000145
RamÃrez-Aragón, M. G., Troyo-Diguez, E., Preciado-Rangel, P., Borroel-GarcÃa, V. J., GarcÃa-Carrillo, E. M., & GarcÃa-Hernández, J. L. (2022). Antioxidant profile of hot and sweet pepper cultivars by two extraction methods. Horticultura Brasileira, 40(4), 411-417. https://doi.org/10.1590/s0102-0536-20220409
Shaimaa, G., & Mahmoud, M. (2015). Phytochemical Screening, Antioxidant Activities and In Vitro Anticancer Potential of Egyptian Capsicum Spp. Biochemistry & Pharmacology: Open Access, 05(02). https://doi.org/10.4172/2167-0501.1000205
Shetty, K., & Sarkar, D. (Eds.). (2020). Functional foods and biotechnology: Sources of functional foods and ingredients. CRC Press/Taylor & Francis Group.
Sun, F., Xiong, S., & Zhu, Z. (2016). Dietary Capsaicin Protects Cardiometabolic Organs from Dysfunction. Nutrients, 8(5), 174. https://doi.org/10.3390/nu8050174
Szallasi, A. (2022). Dietary Capsaicin: A Spicy Way to Improve Cardio-Metabolic Health? Biomolecules, 12(12), 1783. https://doi.org/10.3390/biom12121783
U.S. Department of Agriculture(USDA). (2019). Food data central. https://www.FoodData Central (usda.gov).
Varghese, S., Kubatka, P., Rodrigo, L., Gazdikova, K., Caprnda, M., Fedotova, J., Zulli, A., Kruzliak, P., & Büsselberg, D. (2017). Chili pepper as a body weight-loss food. International Journal of Food Sciences and Nutrition, 68(4), 392-401. https://doi.org/10.1080/09637486.2016.1258044
World Health Organization (WHO). (2018). Non-communicable Diseases (NCD) Country Profiles. Online. https://www lso_en.pdf (who.int).
World Health Organization (WHO). (2022). Non-communicable diseases. https://www.who.int/news-room/fact-sheets/detail/noncommunicable-diseases
Xiang, Y., Xu, X., Zhang, T., Wu, X., Fan, D., Hu, Y., Ding, J., Yang, X., Lou, J., Du, Q., Xu, J., & Xie, R. (2022). Beneficial effects of dietary capsaicin in gastrointestinal health and disease. Experimental Cell Research, 417(2), 113227. https://doi.org/10.1016/j.yexcr.2022.113227
Yang, N., Galves, C., Racioni Goncalves, A. C., Chen, J., & Fisk, I. (2020). Impact of capsaicin on aroma release: In vitro and in vivo analysis. Food Research International, 133, 109197. https://doi.org/10.1016/j.foodres.2020.109197
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2023 Mamakase Grace Sello, Teboho Lekatsa
This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution (CC-BY) 4.0 License that allows others to share the work with an acknowledgment of the work's authorship and initial publication in this journal.