CORRELATES ASSOCIATED WITH ADHERENCE AMONG FEMALE SEX WORKERS ON HIV PRE- EXPOSURE PROPHYLAXIS IN NAIROBI CITY COUNTY, KENYA
DOI:
https://doi.org/10.47604/jhmn.1401Keywords:
Correlates, Adherence, Female Sex Workers, PrEPAbstract
Purpose: The main aim of the study was to assess correlates associated adherence among Female Sex Workers on PrEP in the study. This was done through determining level of knowledge on PrEP, level of adherence, correlates affecting adherence and analysis of strategies to enhancing PrEP adherence.
Materials and Methods: A cross sectional analytical study with mixed method using both qualitative and quantitative data collection method was carried out between March and May 2021. Three hundred and forty-five Female Sex Workers (FSWs) were enrolled in the study. Data was collected using structured questionnaire from study participants after having their consent. Three focus group discussions (FGD) were conducted for those FSWs who will not be involved in the quantitative arm of study. Key Informant Interview was conducted with service providers using Key informant interview (KII) guide. Data collected was entered into Excel spread sheet in password protect computer. Data analysis was carried out in, Univariate analysis, bivariate analysis and multivariate analysis. Statistical Package of Social Science (SPSS) version 20.0 was used for analysis. Data was presented using graphs and Tables.
Results: The study found that 72% did not know the name of PrEP, 39% reported to have missed PrEP with 33% having missed appointment for PrEP refill. Qualitative data showed that PrEP engagement meetings should be conducted monthly to enhance PrEP adherence. The respondents who had reminders on when to take medication was as well associated with adherence (p=0.014) compared with those not using reminders. The study also found out that employment status was associated with adherence to PrEP medication (P=0.050) with FSW who were salaried being 2.5 times more likely to adhere to PrEP medication compared to those who were not salaried.
Unique contribution to theory, practice and policy: The Ministry of Health should ensure that targeted PrEP counselling is done during the initiation for the eligible clients. The information and telecommunication department to work on SMS reminder system in order to remind FSWs using PrEP about appointment dates for the pill pick up thus enhance adherence to FSWs using PrEP. The procurement department should work together with pharmacy department to ensure that there is enough stock for PrEP at every clinic. This will help to ensure that adherence is achieved for the FSWs on PrEP.
Downloads
References
Anandi N Sheth, C. P. (2016). HIV pre-exposure prophylaxis for women. Virus Eradication , 149-155.
B, H. (2015). Pre Exposure Prophylaxis-related Stigma: strategies to improve uptake and adherence. 241-249.
Bartholow B. Valleroy L., M. D. (2000). International Conference on AIDS. Int Conf AIDS , 9-14.
Brydon, C. (2016). PrEp should be a key component of a comprehensive HIV prevention package fully funded on the NHS. The PHARMACEUTICAL JOURNAL .
Carlos F. Florence K, P. g. (2017). The Promises and challenges of pre-exposure prophylaxis as part of emerging paradigm of combination HIV prevention. J Int AIDS SOC .
Florence M. Koechlin, V. A. (2017). Values and Preferences on the use of Oral Pre Exposure Prophylaxis (PrEP) fo HIV Prevention Among Multiple Populations. AIDS and Behavior , 1325-1335.
Fonner, V. A. (2016). Effectiveness and safety of oral HIV preexposure prophylaxis for all population. international AIDS Society , 1973-1983.
Group, N. (2012). Preexposure Prophylaxis for HIV Prevention. The NEW ENGLAND JOURNAL of MEDICINE , 462-465.
Jade F, M. S. (2017). Global Epidemiology of HIV. Infect DIS Clin North Am 2014 (3) : , 323-327.
Jenniffer L. Syvertsen, A. M. (2016). The Promie and Peril of Pre-Exposure Prophylaxis: Using social Science to inform PrEP interventions among Female Sex Workers. Afr J Reprod Health. , 74-83.
Kiragu M., K. J. (2017). Introducing Pre Exposure Prophylaxis in combination prevention. 7-8.
Li Ye, S. W. (2017). HIV Pre-Exposure Prophylaxis Interest among Female Sex Workers in Guangxi, China. plos.org .
Linda B, L. J. (2016). combination HIV prevention for female sex workers: what is the evidence? HIV and Sex workers 2 , 0140-6736.
Martin et al (2017) Factors associated with the uptake of and adherence to HIV pre-exposure prophylaxis in people who have injected drugs: an observational, open-label extension of the Bangkok Tenofovir Study
NASCOP. (2016). PRE EXPOSURE PROPHYLAXIS( ORAL PREP). Nairobi: Ministry of Health.
Peter Mwangi Mugo, E. J. (2015). Understanding Adherence to Daily and Intermittent Regimens Among Men Who Have Sex with Men in Kenya. AIDS AND BEHAVIOR , 794-801.
Robyn Eakle, G. B. (2017). HIV Pre-exposure prophylaxisand early antiretroviral treatment among female sex workers in South Africa: Results from a prospective observational demonstrational project. Plos.org .
Van der Elst EM, M. J. (2017). High acceptability of HIV pre-exposure prophylaxis but challenges and use: qualitative insights from a phase 1 trial of intermittent and daily PrEP in at-risk populations in Kenya. AIDS AND BEHAVIOR , 2162-72.
Vikram Sheel K., M. W. (2016). Measuring Adherence to HIV Pre-Exposure Prophylaxis through Dried Blood Spots. Clinical Chemistry .
William C, G. P. (2016). Correlates of Awareness of and willingness to use Pre-Exposure Prophylaxis ( PrEP) in Gay ,Bisexual, and other Men Who Have Sex with Men Who Use Geosocial-Networking Smartphone Application in New YorkCity. AIDS Behav , 1435-1442.
21 Kebaabetswe PM L E McLellan –Lemal E, Henderson FL, Gray SC, et al. ( 2015) Factors associated with adherence and concordance between measurement strategies in an HIV daily oral tenofovir/ emtricitibine as pre-exposure prophylaxis (PrEP) clinical trial Botswana. AIDS Behav., 19 (5) : 758 69. Doi http://dx.doi.org/10.1007/s10461-014-0891-z
22 Pop- Eleches, C., Thirumurthy H. , Habyarimana, J.P. , Zivin, J. G. Goldstein, M. P.,de Walque, D.,..Bangsberg D.R (2011) Mobile phone technologies improve adherence to antiretroviral treatment in resource limited setting: a randomized controlled trial of text message reminders. AIDS (London, England), 25( 6), 825-834. Doi: http://dx.doi.org/10.1080/09540121 2012. 748871.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2021 Edith Amahwa Litiema, Professor Alloys S. Orago, Dr. Daniel Muia
This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution (CC-BY) 4.0 License that allows others to share the work with an acknowledgment of the work’s authorship and initial publication in this journal.
