FACTORS INFLUENCING ANTIRETROVIRAL TREATMENT FAILURE AMONG ADULT HIV PATIENTS ON TREATMENT AT BOMU HOSPITAL -MOMBASA COUNTY
Keywords:
Co-morbidities, ARV treatment, socioeconomic, CD4 counts and viral loadsAbstract
follow up Bomu Hospital, Mombasa County.
Materials and Methods: The study was a cross sectional at initial patient recruitment and retrospective for patient level data. 299 study participants were selected from a total of 18 425 active on ART. Convenient sampling technique was used to select the adult population for study and thereafter it was categorized into two groups. Semi-structured interview schedules were used to obtain demographic information and patients' views on various dimensions of ART services at the hospital.
Results: Using Chi square test of independence (Fisher exact test) it was found that there was significant association at 5% level of significance between viral suppression and some of the social demographic factors namely marital status and age groups. Using multiple logistic regression model to determine which social demographic and social economic factors affect viral suppression, it was found that age groups and marital status are statistical significant at 10% and 5% respectively. The results showed that there was no significant relationship between period of treatment, co infections and viral suppression. There was positive significant relationship between the viral suppression and current CD4 count. The viral suppression was higher among those with high CD4 count.
Unique contribution to theory, practice and policy: Antiretroviral treatment success requires a multidimensional approach to achieve a complete viral suppression. These multidisciplinary team approaches that include doctors, nurses, pharmacists, counselors and family members must be available to coordinate some of the adherence-related activities. This also increases the likelihood that patients will find someone on the care team to whom they can comfortably relate and from whom they can get needed information about their medications
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